Rejuran Injectable Treatment: What It Is, How It Works, and the Pros and Cons
Rejuran is a regenerative injectable treatment designed to improve overall skin quality, texture, and elasticity. Unlike dermal fillers, which add volume, Rejuran works at a cellular level using polynucleotides (PN/PDRN) derived from salmon DNA. These DNA fragments are highly biocompatible, making them gentle on the skin while encouraging your body’s natural ability to heal, repair, and rebuild collagen.
It has become a popular option for clients wanting healthier, smoother, firmer skin, especially those who want a natural, subtle, and long-term treatment rather than instant plumping. It’s often referred to as The Salmon Sperm Facial!
How Rejuran Works
When Rejuran is injected into the dermis, the polynucleotides help:
Stimulate fibroblasts to produce collagen and elastin
Strengthen the skin barrier and improve hydration
Repair micro-damage from ageing, sun exposure, and inflammation
Improve the extracellular matrix to support smoother, tighter skin
Restore overall skin health and resilience
This skin-healing process takes time, which is why Rejuran is typically performed over a series of sessions, followed by maintenance visits.
What Rejuran Can Treat
Rejuran is suitable for patients who want to improve:
Fine lines and early signs of ageing
Uneven texture or rough skin
Enlarged pores
Mild acne scarring
Thin, fragile, or dehydrated skin
Loss of elasticity
General dullness or reduced skin quality
It’s an ideal treatment for people prioritising skin health rather than adding volume.
Pros of Rejuran
1. Improves Skin Quality
Rejuran delivers gradual but noticeable improvements in texture, tone, and smoothness. Skin becomes healthier and more resilient over time.
2. Supports Natural Regeneration
Because it stimulates the body’s own healing processes, results look natural and improve progressively.
3. Minimal Downtime
Most clients experience only mild redness or swelling for 1–2 days.
4. Biocompatible
The polynucleotides used are well tolerated, with a low risk of reaction.
5. Preventative and Corrective
Rejuran can be used to address early signs of ageing or as an ongoing method to strengthen and maintain youthful skin.
Cons of Rejuran
1. Results Take Time
Rejuran does not work instantly. Improvements appear gradually over weeks, not days.
2. Requires Multiple Sessions
A full course generally includes 3–4 treatments spaced weeks apart, followed by maintenance every 6–12 months.
3. Not Suitable for Volume Loss
Clients with deep folds or significant sagging still require fillers, threads, or other lifting modalities.
4. Short-Term Side Effects
Expect small injection bumps, redness, swelling or mild bruising, all typically short-lived.
5. Cost and Commitment
Because it’s a series-based treatment, clients should be prepared for a long-term investment.
6. Individual Results Vary
Outcomes depend on age, baseline skin condition, lifestyle, and sun habits.
What the Procedure Involves
Before Treatment
A full consultation is required to discuss your skin concerns, suitability, expectations, and medical history.
During Treatment
Numbing cream may be applied
The Rejuran solution is injected into multiple points across the treatment area
The appointment usually takes 30–45 minutes
After Treatment
You may experience:
Visible micro bumps for 12–48 hours
Mild swelling, redness, or pinpoint bruising
Avoid intense exercise, heat, sun exposure, saunas, or active skincare for a couple of days.
Results Timeline
Initial improvement: within a few weeks
Best results: 2–3 months after completing a full course
Maintenance: every 6–12 months
Is Rejuran Right for You?
Rejuran may be ideal if you:
Want healthier, smoother, firmer skin
Prefer natural results rather than dramatic changes
Are concerned about texture, fine lines, or early ageing
Want to improve acne scars or enlarged pores
Are committed to long-term skin maintenance
It may not be ideal if you’re seeking:
Immediate results
Significant lifting or contouring
A one-off treatment with no follow-up
Final Thoughts
Rejuran is a powerful option for patients who prioritise long-term skin health, collagen repair, and natural rejuvenation. While it requires patience and multiple treatments, the payoff is smoother, stronger, more youthful skin that improves from within.
Rewa Aesthetics 2025
Disclaimer: Blog posts are for educational purposes only.
All aesthetic treatments come with risks and potential side effects, and not all treatments are suitable for everyone. A thorough consultation is essential to determine what is safe and appropriate for each individual.